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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRMT3 All Species: 18.79
Human Site: S430 Identified Species: 34.44
UniProt: O60678 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60678 NP_005779.1 531 59903 S430 D C H T T S I S D L E F S S D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092890 531 59784 S430 D C H T T S I S D L E F S S D
Dog Lupus familis XP_534089 541 60618 S440 D C H T T S V S A L E F S S D
Cat Felis silvestris
Mouse Mus musculus Q922H1 532 59884 S431 D C H T T S I S D L E F S S D
Rat Rattus norvegicus O70467 528 59401 S427 D C H T T S I S D L E F S S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505718 571 63850 P470 D C H T A S V P D L E F S S D
Chicken Gallus gallus XP_420907 526 59430 L425 D C N A A S T L D L E F S S E
Frog Xenopus laevis Q8AV13 369 42306 F269 D L S F T S P F C L Q V K R N
Zebra Danio Brachydanio rerio Q5RGQ2 419 48204 F319 D L S F T S A F C L Q I Q R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396035 525 60169 T424 T F D L Y K V T K D C V N F S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192186 519 58632 R418 D I S T V Q V R D L D F I T D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82210 366 41153 F266 D A S F T A P F K L V A Q R N
Baker's Yeast Sacchar. cerevisiae P38074 348 39768 Q248 F K L T A K R Q D M I N G I V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.1 90.9 N.A. 89.8 89.2 N.A. 78.8 70.8 35.4 35.7 N.A. N.A. 42.5 N.A. 45
Protein Similarity: 100 N.A. 96.8 95.1 N.A. 93.9 93.9 N.A. 85.9 83.2 49.1 52.3 N.A. N.A. 62.5 N.A. 63.6
P-Site Identity: 100 N.A. 100 86.6 N.A. 100 100 N.A. 80 60 26.6 26.6 N.A. N.A. 0 N.A. 40
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 100 N.A. 86.6 73.3 40 40 N.A. N.A. 20 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 33.1 31.2 N.A.
Protein Similarity: N.A. N.A. N.A. 48.2 43.3 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 24 8 8 0 8 0 0 8 0 0 0 % A
% Cys: 0 54 0 0 0 0 0 0 16 0 8 0 0 0 0 % C
% Asp: 85 0 8 0 0 0 0 0 62 8 8 0 0 0 54 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 54 0 0 0 8 % E
% Phe: 8 8 0 24 0 0 0 24 0 0 0 62 0 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 47 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 31 0 0 0 8 8 8 8 0 % I
% Lys: 0 8 0 0 0 16 0 0 16 0 0 0 8 0 0 % K
% Leu: 0 16 8 8 0 0 0 8 0 85 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 8 8 0 24 % N
% Pro: 0 0 0 0 0 0 16 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 8 0 0 16 0 16 0 0 % Q
% Arg: 0 0 0 0 0 0 8 8 0 0 0 0 0 24 0 % R
% Ser: 0 0 31 0 0 70 0 39 0 0 0 0 54 54 8 % S
% Thr: 8 0 0 62 62 0 8 8 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 8 0 31 0 0 0 8 16 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _